Discover how microtubule stabilization drugs like paclitaxel alter tumor secretome and fibroblast activation in the tumor microenvironment.
Discover how PM534, derived from marine sponges, targets microtubules with a novel mechanism to overcome cancer resistance and shows promising antitumor activity.
Explore the breakthrough science of photoswitchable microtubule inhibitors - light-controlled drugs that precisely target cancer cells while sparing healthy tissue.
Discover how scientists are designing tricyclic thieno[2,3-d]pyrimidines as next-generation microtubule-targeting agents for more precise cancer chemotherapy.
Discover how epothilones, natural compounds from soil bacteria, are transforming cancer treatment by overcoming drug resistance and targeting microtubules.